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Turku study on Male Reproductive Health |
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DEER |
Developmental Effects of Environment on Reproduction |
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Several cohorts of nineteen year old men from the Turku area have been invited to participate in the study and over 1200 men have been examined. Most of the examined cohorts have been invited for follow-up visits with 2-3 years interval. In addition, a group of 270 voluntary fertile men have been examined. For details on the clinical examinations and sample collection, please see column on the left.
Inclusion criteria Young men born in Finland (also mother born in Finland) and living in the Turku area were invited to participate in the study.
Ethical aspects The studies have been approved by the ethics committee of the Hospital District of Southwest Finland and they have been conducted according to the Helsinki II declaration. All participants gave their informed consent to participate in the study.
Sponsors and collaborators Turku University Hospital Academy of Finland Sigrid Jusélius Foundation European Commission University of Copenhagen
Principal investigator Professor Jorma Toppari MD, PhD
Investigators Horte A MD Perheentupa A MD, PhD Rönkä R MD, PhD Sadov S MD Suominen J MD, PhD Vierula M PhD Virtanen HE MD, PhD
Technicians Järvi J special lab. technician
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The study gathers the following information:
Physical examination Height Weight Degree of masculinization External genitals Testicular size Testicular scan with ultrasound Gynaecomastia
Semen samples Semen quality analysis
Blood samples Reproductive hormone levels DNA isolation (subcohort)
Urine sample Chemical levels (subcohort)
Questionnaire Previous health and growth Socio-economic factors Lifestyle factors Diet
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